Abstract: The improvement of communication and information technology has greatly enhanced the observability and controllability of distribution network. It is necessary to further study the operation characteristics of distribution network from the perspective of cyber physical system (CPS). This paper mainly studies the CPS-based integrated modeling and interaction mechanism of distribution network system. Firstly, a unified modeling method is proposed for distribution system and distribution information system. And then the dynamic interactive influence mechanism of distribution network CPS is studied, and the integrated CPS dynamic interaction model of distribution network is constructed using the distributed generation as the intelligent control and processing terminal. Finally, the dynamic impact of communication faults in distribution network CPS on physical links is analyzed and simulated through testing cases, which has proved the validity of the model.